The outbreak strain was characterized by 3 plasmids of 6. Dt104 isolates in the uk are highly resistant to antimicrobial agents, frequently demonstrating a pattern of resistance to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline rtype acssut 1. Salmonella typhimurium dt104 strains are commonly resistant to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline. Typhimurium dt104 has been associated with outbreaks related to beef contamination and resulted in hospitalization rates twice than that of other foodborne salmonellosis gray and fedorkacray, 2002. Salmonella infections of man and animals continue to be a distressing health problem worldwide. Far from disappearing, the incidence of typhoid fever in developing countries may be far higher than we. Pdf an easter outbreak of salmonella typhimurium dt 104a.
Pdf salmonella enterica is a common cause of gastrointestinal. Get a printable copy pdf file of the complete article 1. A recent study in denmark showed that infection with nontyphoidal salmonella was associated with a 2. Two outbreaks of multidrugresistant salmonella serotype. Assembly, biocollections, bioproject, biosample, biosystems, books, clinvar. International salmonella typhimurium dt104 infections, 19922001 article pdf available in emerging infectious diseases 116. Typhimurium dt104 isolates included in this study were collected. A beefassociated outbreak of salmonella typhimurium dt104 in the netherlands with implications for national and international policy volume 5 issue 6. Typhimurium dt104 commonly resistant to at least five and sometimes more antibiotics have regularly caused foodassociated outbreaks of severe gastrointestinal infection anon. A prolonged outbreak of salmonella typhimurium infection related to an. We used a novel hidden markov model tool called rechmm 27 to detect the clusters. A beefassociated outbreak of salmonella typhimurium dt104 in. International salmonella typhimurium dt104 infections. Global genomic epidemiology of salmonella enterica serovar.
Cdc blogs public health matters blog salmonella typhimurium outbreak investigation. The title of this document is salmonella typhimurium after action report. Salmonella typhimurium salmgene project participants. An outbreak of multidrug resistant, quinoloneresistant salmonella enterica serotype typhimurium dt104. The increasing occurrence of antibioticresistant salmonella in cases of human illness is now of major concern. After action report centers for disease control and. Salmonella typhimurium dt104 strains are commonly resistant to ampicillin. Mdr salmonella typhimurium definitive phage type 104 dt104. Typhimurium dt104 has come to comprise up to 15% of all salmonella infections and was especially prevalent in 2001 1921. In the netherlands, about 50 000 cases of nontyphoidal salmonellosis occur annually 17, 18. A prolonged outbreak of salmonella typhimurium infection related. Outbreaks were observed in dairy herds and feedlot cattle in the pacific.
One study estimated that 600 deaths occur per year in the united states alone due to infections with nontyphoidal salmonella serotypes 7. A multidrugresistant strain of salmonella serotype typhimurium known as definitive type 104 dt104 has emerged as an increasing cause of salmonella infections in the united kingdom uk. A beefassociated outbreak of salmonella typhimurium dt104. Results from italy were not presented because routine phage typing was not performed before 2001. Nontyphoidal salmonella causes mild to severe, including lifethreatening, infections.
Enteritidis infections through hens eggs 2,6 and the emergence over the last 2 decades of multidrugresistant mdr salmonella typhimurium definitive phage type 104 dt104. Pdf salmonella enterica serotype typhimurium dt104 isolated. Multidrugresistant salmonella serotype typhimurium. Full text get a printable copy pdf file of the complete article 1. Characterization and genome analysis of novel bacteriophages. Contextsalmonella serotype typhimurium definitive type 104 dt104, with resistance to 5 drugs ampicillin, chloramphenicol, streptomycin, sulfonamides, and t. Use the link below to share a fulltext version of this article with your friends and colleagues. Salmonella typhimurium dt104 outbreak linked to imported minced beef, norway, october november. Commercial laying hens were infected with salmonella typhimurium dt104 strain 16 alternatively via the crop 107 cfu per.867 342 1468 269 322 1128 848 1347 1241 1270 345 340 1187 883 564 150 1555 750 228 361 1448 763 1379 234 1202 1035 290 549 581 480 177 98 711 304 811 67